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LDN is a widely used compounded medication that is considered a safe, cost-effective treatment for those suffering from autoimmune disorders and pain. It helps reduce pain and also reduces inflammation in many conditions. LDN is a pure inhibitor, which allows no narcotic side effects. The chemical structure is almost identical to endorphins that we make naturally called met-enkephalins, also known as OGF (Opioid Growth Factor). LDN is an antagonist at the OGF receptors, and there are OGF receptors on a wide range of cells in the body. LDN binds to the endorphin receptors for about 1 + 1/2 hours, and the blockade lasts about 4 to 6 hours. The effects of LDN are analgesia and reduced inflammation.
LDN is started at a low dose and titrated up depending on each individual’s response. Typically, it is started at 0.5mg per day and titrated up to a target dose of 4.5mg per day. Some patients may have symptom relief at lower doses than 4.5mg per day, while others may need slightly higher doses than 4.5mg per day. Your physician will monitor your progress to help you achieve the best results.
For further information regarding LDN, please visit https://ldnresearchtrust.org/.
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